同病性失眠和睡眠呼吸暂停与中年人口中不受控制的高血压有关
Mio Kobayashi Frisk1, Joel Bergqvist2,3, Sven Svedmyr2,3
1University of Gothenburg Sahlgrenska Academy, Department of Internal Medicine and Clinical Nutrition, Gothenburg, Sweden; mio.kobayashi.frisk@gu.se.
Annals of the American Thoracic Society
|September 8, 2025
概括
同病性失眠和睡眠呼吸暂停 (COMISA) 独立地与不受控制的高血压有关. 认识睡眠健康 认识睡眠健康
科学领域:
- 心脏病学 心脏病学
- 睡眠医学 睡眠医学
- 公共卫生 公共卫生
背景情况:
- 同病性失眠和睡眠呼吸暂停 (COMISA) 与更糟糕的健康结果和更高的死亡率有关.
- 了解COMISA和高血压之间的联系对于心血管健康至关重要.
研究的目的:
- 调查COMISA和不受控制的高血压之间的关联.
- 为了确定睡眠障碍患者不良心血管事件的危险因素.
主要方法:
- 从瑞典心肺生物图像研究 (SCAPIS) 中对3832名参与者的横截面分析.
- COMISA的定义是通过呼吸暂停-呼吸暂停指数 (AHI) >10和失眠严重性指数得分≥15.
- 没有控制的高血压,定义为BP≥140/90mmHg.
主要成果:
- 在一般人群中,COMISA的患病率为3.1%,在OSA患者中为14.5%.
- COMISA 组显示无控高血压的风险显著增加 (OR 1.88).
- 夜间低氧暴露 (T90) 调解了COMISA/OSA和高血压之间的关系.
结论:
- 这项研究表明,COMISA和不受控制的高血压之间存在独立的关联.
- 研究结果强调,需要针对睡眠障碍制定个性化治疗策略.
- 认识到睡眠健康作为一个多维构造对于管理心血管风险至关重要.
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