胎儿干异常 胎儿干异常
Ingo Gottschalk1, Tina Menzel1, Christoph Berg1
1Division of Prenatal Medicine, Gynecological Ultrasound and Fetal Surgery, Department of Obstetrics and Gynecology, University Hospital, Cologne, Germany.
概括
常见的急性先天性心脏缺陷,常见的急性先天性心脏缺陷,常常在产前被忽视. 使用彩色多普勒系统的胎儿心脏检查可以提高检测率,降低产后死亡率和发病率.
科学领域:
- 心脏病学 心脏病学
- 产前诊断 在产前诊断
- 医疗成像医学成像
背景情况:
- 先天性心脏缺陷 (CHD) 影响大约0.8%的新生儿,其中最常见的关键类型是圆柱形异常.
- 干异常涉及输入管和大血管的缺陷,主要影响右心室外流通道,占CHD的25-30%.
- 这些缺陷包括周膜腹腔隔膜缺陷 (VSD),Fallot四重症 (TOF),肺动脉缩与VSD (PAVSD),大动脉的转移 (TGA),双出口右心室 (DORV),和骨干动脉共同体 (TAC).
研究的目的:
- 为了提供一个概述的产前超声波诊断的conotruncal异常.
- 突出系统胎儿心脏检查对于提高检测率的重要性.
- 强调早期诊断对减少不良产后结果的临床相关性.
主要方法:
- 对用于产前超声波诊断的广泛成像材料的审查.
- 在不同的截面平面上对胎儿心脏进行系统和细分检查.
- 使用色彩多普勒与标准成像平面结合使用,包括输出流道.
主要成果:
- 圆柱形异常常常与正常的四室视图有关,导致产前检测率低.
- 尽管存在挑战,但系统的产前查可以提高这些关键心脏缺陷的检测.
- 早期检测至关重要,因为高的产后死亡率和与未检测到的干异常相关的发病率很高.
结论:
- 产前超声波诊断干异常需要一个系统的方法,超出标准的4室视图.
- 整合流出通道视图和彩色多普勒对提高检测率至关重要.
- 增强产前检测干异常对于及时干预和改善患者结果至关重要.
相关概念视频
Teratogenicity
4.0K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
4.0K
Fetal Circulation
2.6K
Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
2.6K
Development of the Heart
2.1K
The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart...
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart...
2.1K
Uterus and Cervix
4.5K
The uterus, commonly called the womb, is a vital reproductive organ in females designed to provide a nurturing environment for the implantation and growth of an embryo. It is shaped like a hollow pear and positioned between the urinary bladder and the rectum. The uterus's structure allows it to support and protect a developing fetus throughout pregnancy.
The uterus is securely anchored within the pelvic cavity by paired broad ligaments on either side. It is further stabilized by three pairs...
The uterus is securely anchored within the pelvic cavity by paired broad ligaments on either side. It is further stabilized by three pairs...
4.5K
Neurulation
45.4K
Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...
45.4K
Cardiovascular System Abnormal Findings II: Auscultation
564
Auscultation, an essential part of a heart examination, is done using a stethoscope. It provides crucial information about heart function and possible heart problems. Due to heart problems, abnormal sounds can be heard during systole or diastole. These sounds include S3 and S4 gallops, opening snaps, systolic clicks, and murmurs.
Abnormal Heart Sounds
Gallops:
Abnormal Heart Sounds
Gallops:
564


