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在Nocardicin生物合成中,3-Amino-3-carboxypropyl转移的结构基础

Yaojie Gao1,2, Masayuki Karasawa3, Zhiyang Quan4

  • 1Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-0033, Japan.

Journal of the American Chemical Society
|September 8, 2025
PubMed
概括

在酶反应中,S-Adenosyl-l-methionine (SAM) 充当3-氨基-3-碳酸 (3-ACP) 的供体. 这项研究揭示了由NAT酶转移3-ACP的结构基础和机制,提高了我们对这一生物过程的理解.

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