加利福尼亚州产前阿片类药物使用障碍的趋势,2010-2022年
Sidra Goldman-Mellor1, Jyotishman Pathak2, Claire E Margerison3
1Department of Public Health, School of Social Sciences, Humanities and Arts, University of California, Merced, Merced, California; Health Sciences Research Institute, University of California, Merced, Merced, California.
American journal of preventive medicine
|September 8, 2025
概括
在2010年至2022年期间,出生前阿片类药物使用障碍的患病率在加利福尼亚州翻了一番,但大部分增加发生在芬太尼之前.
科学领域:
- 围产期健康 围产期健康
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 在美国,围产期人口中与阿片类药物相关的死亡人数急剧上升.
- 非法芬太尼对产前阿片类药物使用障碍的影响在很大程度上是未知的.
- 加利福尼亚州从2019年开始经历了随后的芬太尼流入.
研究的目的:
- 调查加利福尼亚州芬太尼流入与产前阿片类药物使用障碍之间的联系.
- 分析加利福尼亚州孕妇中阿片类药物使用障碍的趋势.
主要方法:
- 对加利福尼亚州活产分娩 (2010-2022) 的生态,重复的回顾性队列研究 (2010-2022).
- 使用全州,全付款人链接住院和急救部门记录.
- 使用ICD-9-CM/ICD-10-CM诊断和连接点/逻辑回归检查了产前阿片类药物使用障碍的患病率.
主要成果:
- 从2010年到2022年,产前阿片类药物使用障碍的患病率翻了一番 (分娩时为0.15% - 0.30%;通过ED访问为0.04% - 0.08%).
- 大多数增长发生在2018年之前;2018年后的变化是最小的.
- 在非西班牙裔白人,其他/多种族个人和医疗补助受益者中发现了患病率的差异.
结论:
- 芬太尼在加利福尼亚州的引入与产前阿片类药物使用障碍的仅轻微增加有关.
- 持续监测这些趋势对于保护围产期健康至关重要.
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