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Updated: Jan 18, 2026

A Package of Established Analytical Tools to Investigate the Solid-State Alteration of Lipid-Based Excipients
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基于脂质的配方的新发展:通过近红外高光谱成像可视化改善了可湿性和同质的API固体分散

Elizabeta Atanaskova1, Johannes Poms2, Matthias Wolfgang2

  • 1Ss. Cyril and Methodius University in Skopje, Faculty of Pharmacy, Institute of Pharmaceutical Technology, Majka Tereza 47, 1000 Skopje, Republic of North Macedonia; Research and Development, Alkaloid AD, Blvd. Aleksandar Makedonski 12,1000 Skopje, Republic of North Macedonia.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
|September 8, 2025
PubMed
概括

这项研究开发了一种优化的基于脂质的配方,使用脂肪酸的多糖醇 (PGFA) 和六糖醇 (PG6) 来增强药物的溶解性和分散性. 近红外高光谱成像 (NIR-HSI) 有效地优化了费洛迪平的分散,以改善药物释放.

关键词:
化学测量建模化学建模同质性分析是一致性分析.这是一种基于脂质的配方.接近红外的高光谱成像 (NIR-HSI)湿透性 湿透性 湿透性

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