左心室血栓复发的临床预测因素和预后影响
Aloysius Sheng-Ting Leow1, Christopher Junyan Low2, Fang-Qin Goh1
1Department of Cardiology, National University Heart Centre Singapore, Singapore.
Heart (British Cardiac Society)
|September 8, 2025
概括
左心室血栓 (LVT) 复发发生在11.8%的患者中. 活跃的恶性瘤和初始的LVT特征预测复发,这与预后不佳和不良结果有关.
科学领域:
- 心脏病学 心脏病学
- 心血管成像 - 心血管成像
- 血栓形成研究研究
背景情况:
- 有限的当代数据存在于左心室血栓 (LVT) 复发.
- 了解LVT复发对于管理患者的血栓后解决至关重要.
研究的目的:
- 评估LVT复发的发生率和结果.
- 在初始解决方案后确定LVT复发的预测因素.
主要方法:
- 追溯性队列研究,对346名 LVT 患者进行了回顾.
- 随访时间为4.4年,对急性心肌梗塞 (AMI) 后患者进行亚组分析.
- 多变量回归分析,考虑竞争性风险.
主要成果:
- 总体而言,LVT复发的发生率为11.8%,在AMI后的患者中为12.0%.
- 活跃/以前的恶性瘤 (aSHR 5.59-13.9) 和初始的LVT大小/突起预测复发.
- LVT复发显著增加了复合不良结果 (aHR2.77-3.04).
结论:
- 活跃或先前的恶性瘤和初始的LVT成像特征与复发的LVT有关.
- LVT 复发是 LVT 已消失的患者预后不良的标志物.
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