可摄入生物传感器用于药物输送监测
Niha Ansari1, Jeet Dasgupta1, Divyant Jain1
1School of Forensic Science, National Forensic Sciences University, Gandhinagar, Gujarat, India.
Progress in molecular biology and translational science
|September 8, 2025
概括
可摄入生物传感器是胃肠道中的小型电子设备,可实时监测健康参数和药物摄入量. 未来的应用有望通过先进的诊断和远程护理来实现个性化和预防性医学.
科学领域:
- 生物医学工程 生物医学工程
- 数字健康数字健康
- 精密药物疗法 精密药物疗法
背景情况:
- 可摄入生物传感器是小型电子设备,在胃肠道内运行.
- 它们可以实时监测药理和生理参数.
- 从早期无线电药丸到现代FDA批准的SmartPillTM和IntelliCapTM等平台的进步,展示了传感器集成,无线遥测和微电子技术的进步.
研究的目的:
- 概述可摄入生物传感器的开发和应用.
- 要突出它们在检测药物动力学特征,监测代谢生物标志物 (葡萄糖,乳酸盐,挥发性气体) 和验证药物摄入中的作用.
- 讨论它们在行为医学,法医毒理学,临床药理学和慢性疾病管理中的关键应用.
主要方法:
- 讨论核心工程方面,包括数据传输,传感器模块和电源系统.
- 探索诸如生物降解囊,人工智能集成分析平台和生物燃料驱动的传感器等进步.
- 分析诸如电力限制,患者接受,信号减弱和数据隐私问题等挑战.
主要成果:
- 可吞的生物传感器可促进肠道内的实时监测.
- 应用对于各种医学领域至关重要,包括慢性疾病管理和临床药理学.
- 像人工智能集成和可生物降解囊这样的新兴技术正在为下一代医疗保健铺平道路.
结论:
- 可摄入生物传感器有可能对个性化和预防性医学做出重大贡献.
- 这些设备可以重新定义诊断,药物输送和远程监测,从新奇到标准护理的过渡.
- 生物传感器数据与人工智能和大数据平台的整合支持预测诊断和分散护理.
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