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Updated: Jan 18, 2026

Heteromulticellular Stromal Cells in Scaffold-free 3D Cultures of Epithelial Cancer Cells to Drive Invasion
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原异质性:一个障碍和桥梁驱动瘤免疫微环境重塑

Yewen Xie1, Pengyu Chen1,2, Chunjian Qi3

  • 1Laboratory of Oncology, Changzhou Medical Center, The Second People's Hospital of Changzhou, The Third Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, Changzhou, 213003, China.

Immunologic research
|September 8, 2025
PubMed
概括

在瘤微环境 (TME) 中改变原蛋白代谢可以将"冷"瘤转化为"热"瘤. 这种方法可以增强抗瘤免疫力,并通过调节原沉积和免疫细胞透来改善治疗反应.

关键词:
原蛋白的亚型 原蛋白的亚型免疫逃逸是一种免疫逃避.免疫治疗是一种免疫疗法.矩阵改造 矩阵改造瘤微环境是一个微环境.

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