在患有慢性便秘的患者中,高分辨率的阳门测量概况与对照组相比较
Rahul Deshmukh1, Shubham Jain1, Saurabh Bansal1
1Department of Gastroenterology, Topiwala National Medical College and Bai Yamunabai Laxmanrao Nair Charitable Hospital, Mumbai, 400 008, India.
慢性便秘 (CC) 患者与健康志愿者 (HV) 相比,表现出不同的高分辨率门测量 (HRAM) 档案. 功能性排便障碍 (FDD) 和直肠过敏性在CC中普遍存在,类型-1直肠门失能是最常见的FDD亚型.
科学领域:
- 胃肠病学 胃肠病学
- 身体生理学 身体生理学
- 诊断成像 诊断成像 诊断成像
背景情况:
- 我们的人群中慢性便秘 (CC) 的比较研究有限.
- 这项研究通过比较高分辨率门测量 (HRAM) 结果来弥补这一差距.
研究的目的:
- 为了比较CC患者和健康志愿者 (HV) 之间的HRAM个人资料.
- 为了比较功能性排泄障碍 (FDD) 的和没有功能性排泄障碍 (FDD) 的CC患者之间的HRAM概况.
主要方法:
- 对120名CC患者和60名HV患者进行了回顾性比较研究.
- 使用HRAM和气球驱逐试验 (BET).
- 使用基于异常HRAM和BET的ROME-IV标准诊断出FDD.
主要成果:
- CC患者的最大门挤压压力和直肠感觉体积高于HV.
- CC患者的道松,排便指数和直压力梯度的中位数显著降低.
- 在57.5%的CC患者中诊断出FDD,其特征是较高的门余压和较低的直式压力梯度.
结论:
- 在CC患者和HV患者之间,临床和测力学特征存在显著差异.
- 在CC患者中,FDD和直肠过敏更常见.
- 类型-1直失能症是这个队列中占主导地位的FDD亚型.
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