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Updated: May 12, 2026

Induction of Protein Deletion Through In Utero Electroporation to Define Deficits in Neuronal Migration in Transgenic Models
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Nr4a2,一个控制前脑Car3神经元发育和功能维护的关键因素

Yun-Chao Tao1, Li Zhao1, Qiong Zhang2

  • 1State Key Laboratory of Brain Function and Disorders, MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, 200032, China.

Neuroscience bulletin
|September 8, 2025
PubMed
概括

核受体子家族4组A成员2 (Nr4a2) 调节前脑Car3神经元的发育和功能. 这些神经元中Nr4a2的丧失导致过度活跃和减少焦虑.

关键词:
一辆汽车3 汽车3没有4a2焦虑 焦虑是一种焦虑.发展发展发展 发展发展功能维护 维护 功能维护

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In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...