可持续来源的黄纳米颗粒增强了黄素的胃肠道生物可用性
Minghe Wang1, Xiping Gong1, Hualu Zhou1
1Department of Food Science and Technology, College of Agricultural and Environmental Sciences, University of Georgia, Griffin, GA 30223, USA.
Food research international (Ottawa, Ont.)
|September 9, 2025
概括
新开发的黄纳米粒子显著提高了黄素的生物可用性和稳定性. 这种原始到纳米的策略,特别是在纳米乳液中,通过在消化过程中保护黄素来增强黄素的吸收.
科学领域:
- 食品科学 食品科学 食品科学
- 纳米技术纳米技术
- 药理学 药理学是指药理学的学科.
背景情况:
- 来自黄的黄素具有已知的健康益处,但由于溶解性低和快速降解,其生物利用性差.
- 一个新的原料到纳米战略允许直接配制黄纳米颗粒,使用天然生物聚合物进行黄封装和保护.
- 这些黄纳米颗粒对胃肠道命运和食物矩阵的影响在很大程度上仍未得到研究.
研究的目的:
- 通过原料到纳米的战略来研究黄纳米颗粒的胃肠道消化.
- 评估纳米乳液食品矩阵对这些纳米颗粒中的黄素稳定性和生物可用性的影响.
- 为了比较黄纳米颗粒与黄水晶的胃肠道性能.
主要方法:
- 黄纳米粒子 (∼0.11μm) 使用原料到纳米的策略来制备.
- 纳米乳液是作为一种包含黄纳米颗粒的食品模型而制定的.
- 一个体外消化模型被用来检查黄素的胃肠道命运,稳定性和生物可访问性,用黄素晶体作为对照.
主要成果:
- 黄纳米颗粒在消化过程中显示尺寸增加,但在纳米乳液中保持稳定.
- 与黄晶体相比,黄的稳定性在黄纳米颗粒中显著提高,在纳米乳液中达到92.2%左右.
- 黄素的生物可访问性在黄纳米颗粒 (∼66.8%) 显著高于晶体 (∼9.0%),由于混合微粒中的纳米封装,在纳米乳液中进一步改善到∼82.5%.
结论:
- 原料到纳米的策略有效地产生黄纳米颗粒,增强黄素的胃肠稳定性和生物可访问性.
- 将其纳入纳米乳液进一步提高了黄素的稳定性和生物可访问性,证明了食品矩阵的积极影响.
- 黄纳米颗粒代表了一种有前途的方法,用于改善功能性食品和营养保健品中的黄素输送.
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