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1000名脑脊柱角瘤患者的微手术结果:一个全面的队列分析

Joshua Lee¹, Michael G Brandel¹, Benjamin T Ostrander¹

¹Department of Otolaryngology-Head and Neck Surgery, University of California, San Diego, La Jolla, California, USA.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

|September 9, 2025

概括

脑小角瘤的微手术切除表明,在保护面部神经功能和听力方面,成功率很高. 这项对1000名患者的研究强调了对这些复杂的大脑瘤的微手术的有利结果.

科学领域:

神经外科神经外科
在瘤学瘤学.
听力学听力学是指听力学.

背景情况:

大脑角 (CPA) 瘤是手术上具有挑战性的病变.
微手术切除是CPA瘤的主要治疗方式.
评估结果对于优化患者护理至关重要.

研究的目的:

总结1000次连续的CPA瘤微手术切除的结果.
评估影响功能保存和并发症的因素.
提供有关不同手术方法疗效的数据.

主要方法:

对1000名接受CPA瘤微手术切除的患者进行了回顾性队列研究 (2017年11月 - 2024年8月).
分析包括患者/瘤特征,切除程度 (体积测量),面部神经功能 (House-Brackmann分数),听力保存和并发症.
手术方法包括跨实验室 (TL),逆体 (RS) 和中腔 (MCF).

主要成果:

平均年龄49岁,62%是女性. 瘤大小中位数为19毫米. 方法:46.5%的TL,24.6%的RS,24.1%的MCF. 这是一个很好的方法.
88%的患者实现了≤2%的剩余瘤体积. 平均98%的体积减少.
手术后并发症:10%的脑脊髓液泄漏. 面部神经功能 (HB I/II) 在88% (改善到90%). 听力保护: 62% (MCF) 与33% (RS) 相比.

结论:

对CPA瘤的微手术切除产生了有利的结果.
面部神经功能和听力保护受到瘤大小和手术方法的显著影响.
对于较小的瘤来说,关于听力保存,中骨的方法最有效.

关键词:

声学神经瘤是一种声学神经瘤.脑小角瘤脑小角瘤显微外科手术的结果前立腺神经瘤 (Vestibular schwannoma) 是一种前立腺神经瘤.

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