在患有神经髓炎光学谱系障碍的人群中描述金融毒性
Justin B Hill1, Maya L Mastick1, Horacio Chiong-Rivero2
1Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.
概括
在神经髓炎光学谱系障碍 (NMOSD) 中,金融毒性是常见的. 更高的残疾,频繁的攻击,非白人种族和双重阴性血清状态与增加的财务压力有关.
科学领域:
- 神经学 神经学
- 卫生经济学 卫生经济学
- 健康差异 在健康上的差异
背景情况:
- 财务毒性 (FT) 和健康的社会决定因素 (SDOH) 在神经髓炎光学谱系障碍 (NMOSD) 中未得到充分研究.
- 了解这些因素对于全面的患者护理至关重要.
研究的目的:
- 在NMOSD患者中描述FT的患病率.
- 确定与NMOSD中FT相关的社会人口统计和临床特征.
主要方法:
- 进行了一项横截面的匿名调查,对124名美国成年人进行了NMOSD诊断.
- 金融毒性综合评分 (COST) 工具测量了FT,较低的分数表明毒性更高.
主要成果:
- 75%的参与者经历过FT (COST < 25).
- 更高的发作频率,增加的残疾 (患者确定的疾病阶段),非白人种族和双阴性抗体状态与更高的FT有显著的关联.
- 调解分析表明,收入部分调解了残疾和种族对FT的影响.
结论:
- 在NMOSD中,金融毒性非常普遍.
- 关键的临床和社会人口因素对FT有所贡献,突出显示了需要综合护理模型来应对NMOSD管理中的财务挑战.
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