在患有甲状腺功能低下症的患者中评估肺功能测试
Nanak Laha1, Manoj Kumar Prasad1, Brajesh Mishra2
1Department of Medicine, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.
甲状腺功能低下会损害肺功能,增加限制性肺病的风险. 肺功能测试显示,甲状腺功能低下患者的肺容量减少,与较低的甲状腺激素水平有关.
科学领域:
- 内分泌学 在内分泌学.
- 肺部病理学 肺部病理学
- 临床医学 临床医学
背景情况:
- 甲状腺功能低下症与疲劳和运动不耐受等症状有关.
- 肌肉衰弱和肺功能障碍甚至可以发生在亚临床甲状腺功能下降症中.
研究的目的:
- 在患有甲状腺功能低下症的患者中评估肺功能测试 (PFT).
- 研究甲状腺激素水平与肺功能之间的关系.
主要方法:
- 一项涉及136名甲状腺功能低下患者的横截面观察性研究.
- 用ELISA测量的甲状腺特征 (TSH,T3,T4).
- 进行了肺功能测试 (精神测量:FEV1,FVC,FEV1/FVC,PEFR).
主要成果:
- 在75.74%的患者中观察到一种主要的限制性肺功能模式.
- 低峰呼气流速 (PEFR) 表明有限制性肺病.
- 在血清T4和FVC (P=0.006) 和血清T3和PEFR (P=0.041) 之间发现了正相关性.
结论:
- 肺功能测试在甲状腺功能低下症中受到显著影响.
- 甲状腺功能低下患者患有限制性肺病的风险增加.
- 较低的甲状腺激素水平与较差的肺功能有关.
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