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结构引导循环接种改善了流感神经氨基酶的表达和稳定性,用于疫苗开发

Pramila Rijal1,2, Leiyan Wei1,2, Guido C Paesen3

  • 1Chinese Academy of Medical Science Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.

eLife
|September 9, 2025
PubMed
概括

现在可以开发一种稳定的流感神经aminidase (NA) 疫苗. 将NA循环植入稳定的支架上可以改善表达和稳定性,诱导对流感的保护性免疫力.

关键词:
传染病是一种传染性疾病.流感 流感 流感 流感 流感流感病毒是流感的病毒.循环接种 循环接种微生物学的微生物.分子生物物理学分子生物物理学神经aminidase 的使用情况.蛋白质表达 蛋白质表达结构生物学结构生物学疫苗 疫苗 疫苗 疫苗病毒病毒病毒病毒.

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