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Updated: Jan 6, 2026

Myeloid Innate Signaling Pathway Regulation by MALT1 Paracaspase Activity
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多原子分析揭示了BCAT1在mTOR激活中由B细胞受体和TLR9发挥的关键作用

Rui Guo1,2,3, Yizhe Sun1,2,3, Matthew Y Lim4,5

  • 1Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.

The Journal of clinical investigation
|September 9, 2025
PubMed
概括

这项研究揭示了B淋巴细胞如何利用新陈代谢来激活和分化. 抑制BCAT1,一个关键的酶,有效地准B细胞驱动的癌症和自身免疫性疾病.

关键词:
适应性免疫是一种适应性免疫.氨基酸代谢 氨基酸代谢细胞生物学 细胞生物学淋巴瘤是一种淋巴瘤.代谢过程中的代谢.

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