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Updated: Jan 18, 2026

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风险评分轮盘:对多基因风险评分可靠性的警告故事

Diane Xue1, Elizabeth E Blue2,3,4, Alexis C Wood5

  • 1Department of Genetics, University of Pennsylvania, Philadelphia, PA, USA.

Journal of Alzheimer's disease : JAD
|September 9, 2025
PubMed
概括

对阿尔茨海默病 (AD) 的多基因风险评分 (PRS) 在不同模型中显示个体级别可靠性较低. 这种不一致性引发了人们对在临床干预中使用PRS进行AD风险评估的担忧.

关键词:
阿尔茨海默病的疾病阿尔茨海默病的疾病.多基因风险评分多基因风险评分.可靠性的可靠性翻译工作的翻译工作.

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