在精神分裂症频谱中进行补偿性认知训练:在墨西哥门诊患者样本中进行试点研究
Jesús Luna-Padilla1, Alejandra E Ruiz-Contreras2, Yvonne Flores Medina3
1Facultad de Estudios Superiores Iztacala, Universidad Nacional Autónoma de México.
Applied neuropsychology. Adult
|September 9, 2025
概括
补偿性认知训练 (CCT) 在墨西哥精神分裂症患者中改善了工作记忆和处理速度. 虽然认知和抑郁症状有所改善,但在这项试点研究中,日常功能没有显著变化.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
背景情况:
- 精神分裂症谱系障碍的特点是负面症状,抑郁症和影响日常功能的认知缺陷.
- 补偿性认知训练 (CCT) 在增强认知,减少负面症状和改善受影响个体的功能方面表现出有效性.
研究的目的:
- 评估CCT对墨西哥精神分裂症谱系障碍的门诊患者的认知功能和日常功能的影响.
- 评估CCT干预后工作记忆,处理速度和抑郁症严重程度的变化.
主要方法:
- 一项试点研究涉及墨西哥22名精神分裂症谱系障碍的门诊患者.
- 参与者每周接受一次为期12周的基于小组的CCT课程.
- 在干预前和后进行认知和功能评估,包括 MATRICS 共识认知电池 (MCCB) 和功能评估简短测试 (FAST).
主要成果:
- 通过MCCB测量的工作记忆 (η2p = 0.37) 和处理速度 (η2p = 0.24) 显著改善.
- 抑郁症症状严重程度显著减少 (η2p = 0.6).
- 在治疗前和治疗后的功能评分中没有发现显著变化.
结论:
- 在墨西哥的精神分裂症患者中,CCT对认知功能,特别是工作记忆和处理速度产生了积极的影响.
- 这种干预也导致了抑郁症症状严重程度的显著下降.
- 需要进一步的研究来探索CCT对该人群的功能结果的影响.
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