关于MIND-NL饮食,荷兰饮食指南和全球认知功能之间的关联,在一个面临认知衰退风险的老年人群中
Sonja Beers1, Marian A E de van der Schueren2, Pol Grootswagers1
1Division of Human Nutrition and Health, Wageningen University & Research, Wageningen, The Netherlands.
The journal of nutrition, health & aging
|September 9, 2025
概括
坚持荷兰的饮食指南,而不是MIND饮食,在70岁以下的成年人中与认知功能有着下降风险的积极关联. 进一步的研究将探索年龄.
科学领域:
- 神经科学是一个神经科学.
- 营养科学 营养科学
- 老年学是指老年学的学科.
背景情况:
- 认知能力下降是老年人群日益关注的一个问题.
- 饮食模式,如地中海-DASH干预神经退行性延迟 (MIND) 饮食和国家饮食指南,正在研究它们在维持认知健康方面的潜在作用.
- 确定有效的饮食策略对于促进健康的衰老和预防神经退行性疾病至关重要.
研究的目的:
- 检查坚持荷兰MIND饮食 (MIND-NL) 和荷兰饮食指南 (DHD2015-指数) 与面临认知衰退风险的老年人全球认知功能之间的关联.
- 探索年龄,性别,教育,社会经济地位和体力活动对这些协会的潜在缓解影响.
- 通过探索性网络分析来确定与认知功能相关的特定饮食成分.
主要方法:
- 一项利用FINGER-NL试验的基线数据进行的横截面研究,其中包括1,135名面临认知衰退风险的老年人 (60-80岁).
- 通过72项食物频率问卷 (FFQ) 评估了饮食摄入量.
- 全球认知功能通过四个神经心理学子测试的复合得分来衡量. 进行了多次线性回归分析,对各种共变量进行调整,并进行了相互作用和子组分析.
主要成果:
- 无论是MIND-NL饮食还是DDH2015-指数都没有显示出与全球认知功能有显著的整体关联.
- 在70岁以下的参与者中,在遵守DHD2015-指数和更好的全球认知功能之间观察到显著的关联 (p=0.048).
- 探索性分析表明,果蔬和维生素E摄入量与全球认知功能之间存在正相关性.
结论:
- 坚持荷兰饮食指南与70岁以下的老年人改善了全球认知功能,这些人面临认知能力下降的风险.
- 研究结果表明,年龄可能会调节饮食模式和认知功能之间的关系.
- 建议进行进一步的纵向研究,以确认这些关联以及年龄的缓和作用.
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