综合的多omics分析剖析了暴露于di-isobutyl phthalate引起的男性生育能力受损

Yang Yang1, Danni Jiang1, Changli Ji2

  • 1Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, 107 Wenhua West Road, Jinan, Shandong 250012, China; Shandong Key Laboratory of Reproductive Health and Birth Defects Prevention and Control, China.

概括

暴露于二异布甲酸盐 (DiBP) 会通过损害丸和损害精子生产来损害男性生育能力. 这项研究揭示了DiBP破坏肠道微生物群并改变关键的基因和代谢物,提供了对其生殖毒性机制的见解.