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Updated: Jan 18, 2026

A Mouse Model to Investigate the Role of Cancer-Associated Fibroblasts in Tumor Growth
06:35

A Mouse Model to Investigate the Role of Cancer-Associated Fibroblasts in Tumor Growth

Published on: December 22, 2020

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调节纤维内素细胞外基质可增强免疫检查点阻塞的抗瘤功效

Kabir A Khan1, Maresa Caunt Mitzner2, William Cruz-Munoz1

  • 1Biological Sciences Platform, Sunnybrook Research Institute, Toronto, ON, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.

Cell reports. Medicine
|September 9, 2025
PubMed
概括

通过整合素α5β1向细胞外基质 (ECM) 增强了T细胞透和免疫疗法的有效性. 这种方法改善了对免疫检查点抑制剂的反应,为癌症治疗提供了新的策略.

关键词:
它们是Atezolizumab.癌症 癌症 癌症 癌症 癌症组合组合组合的组合组合.细胞外矩阵是细胞外矩阵.纤维肌肉生殖素是什么意思整体中的a5b1瘤免疫疗法 免疫疗法

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