炎症性肠道疾病患者的疲劳:一个描述性的横截面研究
Ana M López-Calleja1, Beatriz López-Cauce2, Marisa Iborra Colomino3
1Centro de Enfermedades Inflamatorias Mediadas por la Inmunidad (CEIMI), Hospital General Universitario Gregorio Marañón, Madrid, España; Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, España.
Gastroenterologia y hepatologia
|September 9, 2025
概括
炎症性肠病 (IBD) 患者的疲劳与较低的生活质量,中度疾病活动,焦虑和抑郁有关. 早期发现疲劳和心理社会因素对于全面的IBD护理至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 临床医学 临床医学
- 精神病体医学是一种精神病体医学.
背景情况:
- 炎症性肠病 (IBD) 包括诸如克罗恩病和性结肠炎等慢性疾病.
- 疲劳是IBD患者常见和衰弱的症状,严重影响他们的生活质量.
- 了解导致疲劳的因素对于制定有效的管理策略至关重要.
研究的目的:
- 确定与IBD患者疲劳存在相关的社会人口统计学,临床和心理社会因素.
- 研究IBD患者的疲劳,疾病活动,生活质量,焦虑和抑郁之间的关系.
主要方法:
- 对243名IBD患者进行了前性,横截面描述性研究.
- 收集的数据包括社会人口统计和临床变量,疾病活动,生活质量 (EuroQol-5D-5L,IBDQ-9),疲劳严重程度,焦虑和抑郁.
- 多变量逻辑回归分析,根据性别和疾病持续时间进行调整,用于识别相关因素.
主要成果:
- 在243名IBD患者中,73人 (30.2%) 报告疲劳.
- 与没有疲劳的患者相比,患有疲劳的患者的生活质量得分明显较低.
- 与疲劳独立相关的因素包括中度疾病活动 (OR:4.88),可能的焦虑 (OR:2.16) 和可能的抑郁 (OR:2.86).
结论:
- 在IBD患者中,疲劳与中度疾病活动,焦虑和抑郁症显著相关.
- 与健康相关的生活质量低下是这一群体中疲劳的关键相关因子.
- 为了最佳的IBD患者管理,需要采取全面的方法,包括早期查疲劳和心理社会并发症.
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