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Updated: Jan 18, 2026

Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods
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Analysis of Group IV Viral SSHHPS Using In Vitro and In Silico Methods

Published on: December 21, 2019

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在人类冠状病毒中,nsp7-11多蛋白处理的动力学和对nsp16复合的影响

Kira Schamoni-Kast1,2, Boris Krichel1,2, Tomislav Damjanović1,2

  • 1CSSB Centre for Structural Systems Biology, Deutsches Elektronen Synchroton DESY, Leibniz Institute of Virology, University of Lübeck, Hamburg, Germany.

Nature communications
|September 9, 2025
PubMed
概括

这项研究研究了由主要蛋白酶 (Mpro) 进行的冠状病毒多蛋白处理,揭示了分裂顺序如何影响复制复杂组件. 原生质谱测量量化了潜在治疗标的反应动力学.

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