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在B类GPCR中的结构编码位置偏差信号:专注于PTH类型1受体

Karina A Peña1, Jean-Pierre Vilardaga2,3

  • 1Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Handbook of experimental pharmacology
|September 9, 2025
PubMed
概括

循环AMP (cAMP) 是产生在内体,不仅仅是血膜. 使用连接物准这种位置偏差可以改变由甲状腺激素类型1受体 (PTH1R) 等受体介导的药理反应.

关键词:
有偏差的连接体.内体内体信号传递G蛋白结合受体的受体是G蛋白结合受体的受体.位置偏差信号传输的信号甲状腺上腺激素激素的作用结构动力学 结构动力学

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