评估心力衰竭中的肺高血压与保存的喷射分数
Jenny Jia Ling Cao1, Yogesh N V Reddy2
1Department of Cardiovascular Medicine, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN, 55905, USA.
Heart failure reviews
|September 9, 2025
概括
肺高血压 (PH) 经常源于心力衰竭与保存的喷射分数 (HFpEF). 本综述探讨了在HFpEF患者中评估和治疗PH,并考虑了同时存在的疾病.
科学领域:
- 心脏病学 心脏病学
- 肺部医学 肺部医学
背景情况:
- 肺高血压 (PH) 在临床实践中经常与心力衰竭与保存的喷射分数 (HFpEF) 相关.
- 与HFpEF相关的PH的同时发生使诊断和评估变得复杂,特别是其他PH组的风险因素.
- 了解这种重叠对于有效的患者管理至关重要.
研究的目的:
- 在HFpEF的背景下审查目前对PH的理解.
- 讨论HFpEF相关PH的评估和病理生物学中的新兴概念.
- 在HFpEF患者中概述目前和未来的PH治疗策略.
主要方法:
- 这是一个复习文章.
- 它综合了关于HFpEF和相关的肺高血压的现有文献.
- 专注于诊断挑战,潜在的机制和治疗方法.
主要成果:
- 在当前的临床环境中,HFpEF是PH的最常见原因.
- 诊断的复杂性来自重叠的风险因素和临床表现.
- 病理生物学涉及心脏和肺系统之间的复杂相互作用.
结论:
- 准确的诊断和量身定制的治疗对于在HFpEF中管理PH至关重要.
- 需要进一步研究与HFpEF相关的PH的特定病理生物学.
- 对于患有复杂心血管和肺部疾病的患者,需要综合护理方法.
相关概念视频
Pathophysiology of Heart Failure
3.0K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
3.0K
Pulmonary Hypertension: Classification and Pathogenesis
584
Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
There are various classifications for PH, each relating to different underlying causes and also...
584
Heart Failure VII: Nursing Interventions
425
The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
425
Heart Failure II: Pathophysiology
752
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
752
Heart Failure IV: Classification and Diagnostic Evaluation
323
Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
323
Heart Failure I: Introduction
711
Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
711


