在电子健康记录中确定酒精使用障碍严重程度的水平
Jakob Manthey1,2, Carolin Kilian3,4,5, Ludwig Kraus3,6,7
1Centre for Interdisciplinary Addiction Research (ZIS), Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf (UKE), Martinistraße 52, 20246, Hamburg, Germany. j.manthey@uke.de.
Substance abuse treatment, prevention, and policy
|September 9, 2025
概括
这项研究使用电子健康记录开发了一个五级酒精使用障碍 (AUD) 严重程度等级. 较高的AUD严重程度与更多的并发症有关,特别是心血管和肝脏疾病.
科学领域:
- 医疗信息学 医疗信息学
- 公共卫生 公共卫生
- 成 药物 药物 药物 药物
背景情况:
- 酒精使用障碍 (AUD) 根据DSM-5是一个维度条件,但电子健康记录 (EHR) 中的ICD-10代码使用二进制定义.
- 这限制了在EHR数据中对AUD严重程度及其相关健康负担的细微分析.
研究的目的:
- 使用现有的电子健康记录 (EHR) 数据对酒精使用障碍 (AUD) 严重程度进行分类.
- 调查AUD严重程度的增加水平与并发症疾病的患病率之间的关联.
主要方法:
- 利用了来自德国法定医疗保险的2017-2021年间21,954名成年人酒精特异性诊断的计费数据.
- 根据ICD-10代码将AUD严重程度分为五个级别.
- 使用概括估计方程回归模型来评估与Elixhauser并发症评分 (ECS) 的关联.
主要成果:
- 观察到AUD严重程度和Elixhauser并发症评分 (ECS) 之间的剂量反应关系.
- 患有较高AUD严重程度的个体表现出更多的并发性疾病.
- 心血管和肝脏疾病在AUD严重程度较高的个体中是特别普遍的并发症.
结论:
- 基于ICD-10诊断的AUD严重程度分类系统可以在EHR数据中进行更详细的分析.
- 这种方法支持对AUD对患者健康和并发症的影响有更细微的理解.
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