西班牙前列腺癌积极监测的现实世界证据;中期结果
J Rubio-Briones1, A Borque-Fernando2, L M Esteban Escaño3
1Hospital VITHAS 9 de Octubre, Valencia, Spain.
Cancer medicine
|September 10, 2025
概括
西班牙的积极监测 (AS) 显示了与国际标准相美的中期瘤结果. 然而,没有,有.
科学领域:
- 在瘤学瘤学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 这项研究使用了来自AS的西班牙注册 (AEU-PIEM/2014/0001),一个多中心纵向注册的数据.
- 它专注于2014年至2019年期间注册的一组主动监测 (AS) 患者.
研究的目的:
- 评估西班牙前列腺癌积极监测 (AS) 的中期瘤结果.
- 评估对初始前列腺癌特征的指南建议的遵守情况.
主要方法:
- 分析了3315名AS患者 (低风险和中等风险) 的队列.
- 数据包括患者人口统计,诊断方法 (MRI,活检),随访间隔和临床结果.
- 随访时间中位数为62个月.
主要成果:
- 37%的患者仍然在AS,而8%的患者过渡到警等待.
- 在5年后,无病态进展的存活率为51%;无转移的存活率为99%.
- 在5年内,无活性治疗的生存率为50%.
结论:
- 西班牙AS的中期瘤结果与国际研究结果一致.
- 建议的诊断工具,如MRI和跨关节活检,对于初始前列腺癌的特征性有不足的使用.
- 需要进一步的研究来完善AS协议并确定积极治疗过渡的最佳候选人.
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