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Updated: Jan 18, 2026

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在早期发病和家族性骨髓增殖新生体中,CHEK2生殖系变异

Oscar Borsani1,2, Elisabetta Molteni2, Daniela Pietra2

  • 1Department of Molecular Medicine, University of Pavia, Pavia, Italy.

American journal of hematology
|September 10, 2025
PubMed
概括

在CHEK2的致病性生殖基因突变中,在2.2%的骨髓增殖性新生体 (MPN) 患者中发现了这种突变. 这些CHEK2变种与家族癌症史和患白血病的风险增加有关.

关键词:
CHEK2 是一个国家.细菌线的生殖线骨髓扩散性 骨髓扩散性预备性 预备性 预备性

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