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认知补救对精神分裂症患者的认知和精神病理症状产生积极影响:一项初步研究
Maria Skokou1, Lambros Messinis1, Panagiotis Stavridis2
1Laboratory of Neuropsychology and Behavioral Neurosciences, Department of Psychology, Aristotle University of Thessaloniki, University Campus, 54124, Thessaloniki, Greece.
Applied neuropsychology. Adult
|September 10, 2025
概括
计算机辅助认知康复改善了精神分裂症患者的认知功能. 这种干预增强了注意力,执行功能和流性,表明神经可塑性的潜力.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 康复医学 康复医学 康复医学
背景情况:
- 认知障碍是精神分裂症的核心特征,严重影响日常功能和生活质量.
- 鉴定精神分裂症认知缺陷的有效干预措施对于患者的康复至关重要.
研究的目的:
- 在被诊断为精神分裂症的患者中研究计算机辅助认知康复计划的有效性.
- 评估干预对各种认知领域和临床症状的影响.
主要方法:
- 一项随机对照试验,涉及20名精神分裂症患者,10名在干预组 (REHACOM软件) 和10名在假控制组.
- 参与者接受了为期8周的每两周一次60分钟的会议,以及例行精神病治疗.
- 使用Trail Making Test (TMT) A&B,Verbal Fluency Test (VFT) 和Symbol Digit Modalities Test (SDMT) 测量认知结果. 这两项测试的结果是: 通过PANSS和WHODAS尺度评估的临床结果.
主要成果:
- 与对照组相比,干预组在注意力/处理速度,执行功能和语义流性方面表现出显著的改善.
- 在阳性和阴性综合征尺度 (PANSS) 上的负面,一般和总分有显著的减少.
- 干预组在世界卫生组织残疾评估计划 (WHODAS) 评分上也显示出显著的改善.
结论:
- 初步证据表明,计算机辅助认知康复在改善精神分裂症患者的认知功能方面是有效的.
- 这些发现支持了这种人群中通过认知补救的适应性神经可塑性的潜力.
- 恢复性认知康复可能是精神分裂症管理的有价值的治疗方法.
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