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对非肌肉侵袭性膀癌的阻断切除后重复通过尿道切除的评估

Jincong Li¹, Yuxuan Song¹, Rui Chen¹

¹Department of Urology, Peking University People's Hospital, Beijing, China.

Therapeutic advances in urology

|September 10, 2025

概括

在非肌肉侵入性膀癌 (NMIBC) 的膀瘤封锁切除 (ERBT) 后,可能不需要重复过尿道切除 (reTURB). ERBT有效地管理剩余瘤和升级阶段,这表明在许多NMIBC病例中可以避免reTURB.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
在瘤学瘤学.
手术瘤学手术瘤学

背景情况:

对于非肌肉侵入性膀癌 (NMIBC),常规的膀透尿切除 (TURBT) 往往需要重复 TURBT (reTURBT).
对于NMIBC的膀瘤阻断切除 (ERBT) 后的reTURBT的作用仍然不太被探索.
这项研究调查了在NMIBC患者中ERBT后reTURBT的必要性.

研究的目的:

评估在非肌肉侵入性膀癌 (NMIBC) 的膀瘤阻断切除 (ERBT) 后,是否可以避免重复过尿道切除 (reTURBT).

主要方法:

对NMIBC进行ERBT后的reTURBT研究的系统审查和元分析.
在PubMed,科学网,EMBASE和科克兰图书馆搜索到2024年11月14日.
使用R软件和Cochrane Review Manager进行数据分析;协议注册在PROSPERO (1082989) 上.

主要成果:

包括17项研究,共有1051名参与者.
在ERBT后,残留瘤和上升阶段的发生率分别为9%和0%.
没有观察到reTURBT对无复发生存,复发或进展的显著益处.

结论:

膀瘤块切除 (ERBT) 有效控制了NMIBC中的残留瘤和上升阶段.
在NMIBC患者的ERBT后,可能不需要随后重复的输尿管切除 (reTURBT).

关键词:

在集体切除中切除.非肌肉侵袭性膀癌是非肌肉侵袭性膀癌.重复通过尿道切除.系统性审查系统性审查

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