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长期COVID-19改变了肌肉结构和肌力传递:一项为期一年的纵向研究

Leandro Gomes de Jesus Ferreira^1,2, Isabella da Silva Almeida^1,2, Rochelle Rocha Costa³

¹Laboratory of Muscle and Tendon Plasticity, Graduate Program in Rehabilitation Science, Faculdade de Ciências e Tecnologias em Saúde, Universidade de Brasília, Brasília, Brazil.

Frontiers in physiology

|September 10, 2025

概括

严重的COVID-19感染会在长达一年的时间内改变四头肌肌结构和肌 - 肌神经复杂性质. 这些变化可能解释了持续的弱点,突出了针对性康复策略的需要.

科学领域:

生物医学工程生物医学工程
肌肉骨生理学肌肉骨生理学
传染病研究传染病研究

背景情况:

有限的研究存在于COVID-19对骨肌肉的长期影响.
了解这些影响对于康复和恢复策略至关重要.

研究的目的:

评估中度和重度COVID-19对四头肌肌肉结构和肌神经复合体 (TAC) 属性的一年影响.
将这些变化与健康的对照组进行比较.

主要方法:

70名参与者 (中度COVID-19,严重COVID-19,控制) 在一年内接受了评估.
超声波成像评估了巨大的横侧骨和直腿骨束的长度,笔纹角和在同位数膝盖延伸期间的TAC位移.
概括估计方程模型分析了组和时间效应,并将扭矩作为共变量.

主要成果:

严重的COVID-19导致带长度发生变化,并减少了直骨 femoris和横骨 vastus 的 TAC 位移.
与对照组相比,这两个COVID-19组都显示出更长的广横向囊,并且在静止状态下减少了笔纹角.
在所有组中,扭矩显著影响了角和TAC刚度.

结论:

严重的COVID-19导致持续的肌肉结构变化,感染后长达一年,可能导致肌肉衰弱.
肌肉力量和扭矩是影响肌肉结构和力传递的关键因素.
建议在长期COVID-19康复期间加强四肢,以恢复肌肉功能.

关键词:

在COVID-19大流行中,连带的长度是连带的长度.肌肉超声波肌肉超声波是一种超声波.肌单位是肌单位.标签: 标签: 标签: 标签: 标签: 标签: 标签: 标签: 标签: 标签: 标签:

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