通过将内分泌学与胃肠道疾病联系起来,评估与维生素D缺乏相关的消化问题
Wachi Jain1, M Khaliq2, Abdul Wahab3
1Medicine, Lincoln County Hospital, Lincoln, GBR.
Cureus
|September 10, 2025
概括
维生素D缺乏症常见于胃肠道 (GI) 问题患者,恶化症状并导致内分泌问题. 早期对维生素D和荷尔蒙的测试可以改善胃肠道疾病的管理.
科学领域:
- 胃肠道学和内分泌学
- 营养科学 营养科学
背景情况:
- 维生素D缺乏与肌肉骨疾病有关,影响胃肠道 (GI) 和内分泌健康.
- 胃肠道疾病中维生素D缺乏的患病率和临床意义需要进一步调查.
研究的目的:
- 为了确定维生素D状态和胃肠道症状严重程度之间的关系.
- 评估维生素D缺乏对相关内分泌干扰的影响.
主要方法:
- 一项涉及120名患有胃肠道症状的成年患者的横截面研究.
- 测量了血清25-氧维生素D (25(OH) D),皮质醇和副甲状腺激素 (PTH) 的水平.
- 用经过验证的尺度评估消化道症状,并通过皮尔森相关性分析相关性.
主要成果:
- 81.7%的参与者缺乏维生素D (平均血清水平为16.8 ng/mL).
- 维生素D缺乏与IBS的严重程度增加相关,反流,便秘,腹痛,气体/胀气以及肠道失禁.
- 与脂肪肝指数观察到负相关性;65%的皮质醇和PTH水平升高.
结论:
- 维生素D缺乏症在慢性胃肠道患者中很普遍,与症状严重程度和内分泌干扰有关.
- 将维生素D和荷尔蒙测试纳入诊断可以帮助临床管理功能性胃肠道疾病.
- 早期识别和治疗这些缺陷可以导致个性化和有效的治疗策略.
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