阻塞性睡眠呼吸暂停和腹部外科手术中的术后过敏症:一个前性的观察队列研究
Zhenyu Zhong1, Xian Lu2, Qian Zhang1
1Department of Anesthesiology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, People's Republic of China.
Journal of pain research
|September 10, 2025
概括
患有中度至重度阻塞性睡眠呼吸暂停 (OSA) 风险较高的患者更容易患上手术后的过敏症. 建议早期进行OSA查,以减少术后疼痛并改善患者的治疗结果.
科学领域:
- 麻醉学 麻醉学
- 睡眠医学 睡眠医学
- 疼痛管理 疼痛管理
背景情况:
- 手术后的过敏症 (POH) 是一种常见的并发症,增加了患者的疼痛.
- 确定的POH风险因素包括手术部位,阿片类药物,性别和年龄.
- 阻塞性睡眠呼吸暂停 (OSA) 和POH之间的关联需要进一步调查.
研究的目的:
- 调查OSA严重程度和POH之间的关系.
- 在接受减肥手术的患者中识别POH的危险因素.
主要方法:
- 一项前性观察性研究与接受减肥手术的患者进行.
- 患者根据OSA风险分层使用STOP-Bang问卷.
- 使用VAS评估术后疼痛,并使用弗雷丝丝测量机械疼痛值.
主要成果:
- 在69.1%的患者中诊断出POH.
- POH的独立风险因素包括男性性别,年龄,BMI≥35kg·m-2,中度至重度OSA的高风险,以及较低的手术前机械疼痛值.
- 患有高风险OSA的患者POH的几率明显更高 (OR,6.43;95% CI,2.71-15.52).
结论:
- 患有中度至重度OSA高风险的患者更有可能患POH.
- 在手术后24小时内,高风险的OSA患者中,过敏症的严重程度更大.
- 手术前的OSA查对于缓解POH至关重要.
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