在炎症性肠道疾病患者中,焦虑和抑郁症状的发生率:一个多中心研究
Mohammed Momin Sugie1, Gebeyehu Tessema Azibte2, Ahmed Adem3
1Department of Internal Medicine Dire Dawa University College of Medicine Dire Dawa Ethiopia.
JGH open : an open access journal of gastroenterology and hepatology
|September 10, 2025
概括
炎症性肠病 (IBD) 患者的焦虑和抑郁率较低. 然而,严重的疾病活动显著增加了IBD患者焦虑和抑郁症状的风险.
科学领域:
- 胃肠病学 胃肠病学
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 患有炎症性肠病 (IBD) 的人面临更高的精神疾病风险,影响他们的生活质量.
- 全球证据凸显了IBD和心理健康挑战之间的联系.
研究的目的:
- 确定诊断为IBD的患者焦虑和抑郁症状的患病率.
- 在IBD患者群体中识别与焦虑和抑郁相关的因素.
主要方法:
- 进行了一项基于机构的横截面研究.
- 数据使用千平方测试,沙皮罗-威尔克测试和单变量/多变量二进制逻辑回归来分析.
- 统计学意义设定为p < 0.05,结果以调整的赔率比率 (AOR) 和95%置信区间进行报告.
主要成果:
- 在IBD患者中,焦虑和抑郁症状的患病率分别为5.1%和7.1%.
- 中度和重度的疾病活动与抑郁症状的增加显著相关 (AOR=16.1,p=0.015;AOR=49.8,p=0.014).
- 严重的疾病活动是与焦虑症状相关的重要因素 (AOR=45.3,p=0.016).
结论:
- 虽然整体患病率很低,但疾病活动,吸烟,失业和最近诊断的持续时间是影响IBD焦虑和抑郁的关键因素.
- 性结肠炎亚型也被认为是与症状增加相关的因素.
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