在中部和侧部前额叶皮层中,主动和反应性认知控制的神经动态
Anas U Khan1, Colin W Hoy2,3, Kristopher L Anderson3
1Department of Neurosurgery, University of Alabama at Birmingham, Birmingham, AL, USA.
iScience
|September 10, 2025
概括
认知控制调整到冲突使用大脑活动在dorsomedial前额叶皮质 (dmPFC) 和dorsolateral前额叶皮质 (dlPFC). 试验前dmPFC信号中的theta振荡主动控制,增强目标导向的行为.
科学领域:
- 神经科学是一个神经科学.
- 认知神经科学 认知神经科学
- 计算神经科学是一种神经科学.
背景情况:
- 目标导向的行为需要认知控制来管理冲突.
- 太太振荡和前额叶皮层 (PFC) 活动对于反应性控制至关重要.
- 这些神经机制在主动控制中的作用仍然不太清楚.
研究的目的:
- 在主动控制中,研究度振荡和群体活动在背中PFC (dmPFC) 和背侧PFC (dlPFC) 中的参与.
- 检查冲突预期如何影响Stroop任务期间的神经活动.
主要方法:
- 人类内脑电图 (EEG) 记录在Stroop任务期间.
- 操纵冲突预期,以区分主动和反应控制.
- 在dmPFC和dlPFC中分析,β和高频活动 (HFA).
主要成果:
- 在响应选择过程中,冲突处理在两个区域都增强了dlPFCβ脱同步,dmPFCβ增加和HFA.
- 响应后冲突抑制了theta和提升了β反弹.
- 在试验前,dmPFC θ随着预期的冲突而增加,而在罕见的冲突试验中,theta,beta和HFA动态得到了突出.
结论:
- 反应和主动控制之间的平衡调节了dmPFC和dlPFC中共享的HFA和独特的theta-beta信号.
- 试验前的dmPFC甲基活性是主动认知控制的潜在神经基质.
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