晚上不安的眼睛:不安腿综合征的一个新型变体
Yasutaka Yanagita1, Takanori Uehara1, Koichiro Kishimoto1
1Department of General Medicine, Chiba University Hospital, Chiba, Japan.
European journal of case reports in internal medicine
|September 10, 2025
概括
不安腿综合征 (RLS) 可以在眼睛中表现出来,导致运动缓解的夜间疼痛. 这项案例研究强调了 gabapentin enacarbil 作为这种罕见的眼部 RLS 变体的潜在治疗方法.
科学领域:
- 神经学 神经学
- 眼科医生 眼科 眼科
- 睡眠医学 睡眠医学
背景情况:
- 不安腿综合征 (RLS) 是一种常见的感觉运动障碍,通常影响腿部.
- 影响其他身体部位的非典型RLS变体越来越多地被报告,但眼部参与是未经记录的.
- 运动缓解的夜间眼部疼痛可以表明RLS变种.
研究的目的:
- 报告一种影响眼部区域的新型不安腿综合征病例.
- 描述眼部RLS的临床表现和诊断挑战.
- 为了评估在这种非典型的RLS呈现中治疗反应.
主要方法:
- 一个57岁的女性患有慢性夜间眼痛的详细病例报告.
- 对预期干眼和非典型面部疼痛的先前治疗方法的审查.
- 对多巴胺激动剂 (pramipexole) 和 gabapentin enacarbil 的反应的评估.
主要成果:
- 患者出现了10年的夜间眼睛疼痛,通过眼睛运动或眼刺激来缓解.
- 对眼睛和面部疼痛的标准治疗方法是无效的.
- 患者对 gabapentin enacarbil 的反应很好,但对 pramipexole 的反应不佳.
结论:
- 不安腿综合征可以出现眼部症状,这是以前未经记录的变种.
- 临床医生应考虑在夜间感觉不适的患者中通过运动缓解RLS,即使没有肢体症状.
- gabapentin enacarbil 可能是一个有效的治疗眼部RLS.
关键词:
这种RLS的变体是RLS.焦躁腿综合征是什么意思gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin gabapentin眼部疼痛 眼部疼痛更多相关视频
06:23A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
Published on: September 22, 2020
6.0K
08:58Optogenetic Manipulation of Neural Circuits During Monitoring Sleep/wakefulness States in Mice
Published on: June 19, 2019
10.4K
相关概念视频
Restless Leg Syndrome and Night Terrors
494
Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
494
REM Sleep Behavior Disorder
1.4K
REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
RBD is significantly associated with...
1.4K
Narcolepsy
505
Narcolepsy is a chronic sleep disorder characterized by pervasive, uncontrolled sleepiness and other sleep disturbances. One of its hallmark symptoms is an abrupt transition to REM sleep upon falling asleep, which causes symptoms typically associated with this phase to occur unexpectedly during wakefulness. These include the following symptoms, which typically last from a minute or two to half an hour.
505
Sleep-Wake Cycles
2.7K
Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
2.7K
Photoreceptors and Visual Pathways
8.8K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
8.8K
Nightmares and Night Terrors
474
Nightmares and night terrors represent two distinct types of sleep disturbances that differ in timing, characteristics, and the sleeper's recall of the event. Nightmares are vivid, disturbing dreams that usually awaken the sleeper from REM sleep, a stage of sleep where brain activity is high, and dreams are most frequent. Upon awakening, individuals often have detailed recollections of their nightmares, which can include themes of threats to survival, security, or self-esteem.
Nightmares...
Nightmares...
474
