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测量ADRC UDS数据元素,FDA和EHR数据标准之间的调整.

Zhan Wang1, Kayla Torres1, Helen Foster1

  • 1Department of Population Health Sciences, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.

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概括
此摘要是机器生成的。

阿尔茨海默氏病研究中心统一数据集 (UDS) 数据显示与临床数据交换标准联盟 (CDISC) 标准 (94%) 的高度兼容性以及通过健康水平七 (HL7) 快速医疗互操作资源 (FHIR) (45%) 的电子健康记录 (EHR) 提取的潜力. 这项研究支持跨ADRC研究,电子健康记录和行业的数据共享.

关键词:
阿尔茨海默病和相关痴呆症的研究研究.临床数据交换标准联盟菲希尔 (FHIR) 是一个人.数据重复使用.数据标准的数据标准.

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科学领域:

  • 生物医学信息学 生物医学信息学
  • 健康数据标准 卫生数据标准
  • 神经科学研究 数据管理 数据管理

背景情况:

  • 阿尔茨海默病研究中心 (ADRC) 使用统一数据集 (UDS).
  • 电子健康记录 (EHR) 通常使用健康七级 (HL7) 快速医疗互操作资源 (FHIR).
  • 行业研究经常使用临床数据交换标准联盟 (CDISC) 的标准.

研究的目的:

  • 为了比较和测量ADRC UDS,HL7 FHIR和CDISC标准之间的对齐.
  • 评估将阿尔茨海默病研究数据与临床和行业标准协调的可行性.
  • 确定改善阿尔茨海默病和相关痴呆症 (ADRD) 研究数据标准协调的领域.

主要方法:

  • 采用系统的映射过程,使ADRC UDS数据元素与HL7 FHIR和CDISC标准保持一致.
  • 两个独立的映射器评估了数据元素对齐.
  • 专家的裁决解决了在映射过程中发现的任何差异.

主要成果:

  • 在5959个UDS数据元素中的45%与FHIR标准进行了映射,这表明了EHR数据提取的潜力.
  • 94%的UDS数据元素映射到CDISC标准,表明与行业数据要求的高度兼容性.
  • 该研究确定了加强数据标准协调的具体领域.

结论:

  • 协调ADRC的UDS数据与CDISC和FHIR标准是可行的.
  • 与FHIR相比,CDISC标准与ADRC的UDS数据保持了更好的一致性.
  • 随着资源的成熟和标准化的加强,FHIR显示出改进的潜力,促进了ADRC研究,EHR和行业之间的数据共享.