一般的人口实用性得分是否准确地代表了现实世界体验的健康状况?
J Felipe Montano-Campos1, Anirban Basu2
1School of Pharmacy, CHOICE Institute, University of Washington, 1956 NE Pacific St H362, Seattle, WA, 98195, USA. fmontano@uw.edu.
概括
与健康相关的生活质量 (HRQoL) 相关的社会实用权重与较低健康水平的患者体验不一致. 成本效益分析应纳入患者经验丰富的实用权重,以确保准确性.
科学领域:
- 卫生经济学 卫生经济学
- 患者报告的结果
- 生活质量研究 研究 生命质量研究
背景情况:
- 成本效益分析 (CEA) 通常依赖于健康状况的社会实用权重.
- 这些权重来源于一般人口对假设健康状况的看法.
- 这项研究调查了这些社会权重与现实世界体验到的健康状况之间的一致性.
研究的目的:
- 评估社会实用权重与自我报告的体验健康状况之间的一致性.
- 为了确定一般人群的感知是否准确地反映了患者报告的结果.
- 评估对成本效益分析的影响.
主要方法:
- 自我报告的健康状况与全国代表性调查的比较 (大约. 3万阿根廷人) 获得了与健康相关的生活质量 (HRQoL) 相关的实用权重.
- 利用多项逻辑回归来建模衍生HRQoL与自我报告的健康状况 (差到优秀) 之间的关系.
- 模型选择基于阿卡伊克信息标准 (AIC) 和贝叶斯信息标准 (BIC).
主要成果:
- 在较低的HRQoL值 (<0.16) 中,观察到HRQoL和自我报告的"差"和"好"健康状况之间的非单调关系.
- 具体来说,随着HRQoL的增加",不良"健康的可能性增加,而"良好的"健康的可能性在这个范围内下降.
- 对于"非常好"和"优秀"的自我报告健康,发现了一个积极的单调关系.
结论:
- 社会HRQoL权重与患者报告的结果之间存在显著差异,特别是在较低的健康状态下.
- 这表明一般人群可能低估了严重健康状况的负担.
- 这些发现倡导将患者经历的实用权重纳入成本效益研究.
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