基于EV的骨关节炎无细胞治疗的全球研究趋势:一个图书识别分析
Chuanhui Zhang1, Chen Xu2, Chengshuai Sun3
1Department of Joint and Sports Medicine, Chaoyang Central Hospital, Chaoyang City, Liaoning Province, China. 46952025@qq.com.
Tissue engineering and regenerative medicine
|September 10, 2025
概括
使用细胞外囊泡 (EVs) 的无细胞疗法对骨关节炎 (OA) 治疗有希望. 本文献分析揭示了这个新兴领域的快速增长和关键研究主题.
科学领域:
- 整形外科和再生医学
- 生物技术是生物技术.
- 细胞生物学 细胞生物学
背景情况:
- 骨关节炎 (OA) 造成了严重的全球健康负担,治疗选择有限.
- 目前的骨关节炎治疗侧重于缓解症状或进行关节置换手术.
- 使用细胞外囊泡 (EVs) 的无细胞疗法为软骨修复和骨代谢调节提供了一种新的方法.
研究的目的:
- 对基于骨关节炎 (OA) 细胞外囊泡 (EVs) 的无细胞治疗研究进行第一个文献分析.
- 识别出版趋势,主要贡献者和这个领域的新兴研究方向.
- 为骨科和再生医学专家提供关于基于EV的OA疗法的当前状态和未来潜力的全面概述.
主要方法:
- 从科学网络核心集合中检索的1991年至2024年出版物的图书法分析分析.
- 对出版趋势,主要国家,机构,作者和期刊的分析.
- 确定关键的研究主题和新兴方向在OA无细胞EV治疗.
主要成果:
- 自2019年以来,观察到与OA无细胞EV治疗相关的出版物显著增加.
- 中国在出版量和引用量方面处于领先地位,上海通大学是最具生产力的机构.
- 关键的研究主题包括治疗机制,进步,外体工程和基于电动汽车的药物递送系统.
结论:
- 这项文献计量研究提供了一个全面的视角,即为骨关节炎提供无细胞细胞外囊泡治疗的新兴领域.
- 它强调了快速增长,关键参与者和占主导地位的研究领域,指导了未来的研究和临床应用.
- 这些发现为骨科和再生医学专家提供了宝贵的见解,他们正在探索新的OA治疗策略.
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