儿童不良经历,神经认知功能和长期死亡风险
Jing Yu1, Denise L Haynie1, Rajeshwari Sundaram2
1Social and Behavioral Sciences Branch, Division of Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland.
JAMA network open
|September 10, 2025
概括
儿童的神经认知技能与降低死亡风险有关. 然而,生命早期的严重逆境可能会削弱这些保护性关联,突出显示了弹性因素的重要性.
科学领域:
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 纵向研究表明,较高的智力能力与较低的死亡率相关.
- 以前的研究往往没有充分解释早期生活因素或逆境.
- 神经认知对面临逆境的儿童死亡率的影响仍未得到充分研究.
研究的目的:
- 研究儿童神经认知功能如何与死亡风险相关.
- 为了检查早期生活中的逆境是否会改变神经认知和死亡率之间的关系.
- 了解神经认知发育在不同环境中的长期健康影响.
主要方法:
- 利用了来自协作周产期项目 (CPP) 的数据,这是一项美国队列研究 (1959-1966).
- 评估神经认知技能,包括视觉-运动,感觉-运动,听觉-语音,智商和学术能力.
- 将CPP队列与国家死亡指数联系起来,以追踪到2016年的全因死亡率.
主要成果:
- 在9个神经认知分数中,有8个与降低死亡风险有关.
- 每一个标准偏差增加的神经认知与9%-15%较低的死亡风险相关.
- 保护性关联在智商和算术技能方面是显而易见的,但随着生命早期的严重逆境而减少.
结论:
- 儿童的神经认知功能通常与较低的过早死亡风险有关.
- 严重的早期生命逆境可以减弱神经认知的死亡率保护作用.
- 发展强大的神经认知技能可能会促进长期的健康弹性,即使在逆境中.
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