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CpG-A诱导HMGB1的液-液相分离,以激活RAGE介导的炎症途径

Kaihui Peng1, Gaohong Fu1, Long Chen1

  • 1State Key Laboratory of Green Biomanufacturing, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China.

Proceedings of the National Academy of Sciences of the United States of America
|September 10, 2025
PubMed
概括

高流动性组盒子蛋白1 (HMGB1) 与细菌DNA相互作用,触发液体-液体相分离 (LLPS). 这个过程激活了免疫信号通路,在微生物感染反应期间释放炎症性细胞因子.

关键词:
这就是HMGB1的特点.愤怒的愤怒 愤怒的愤怒炎症,炎症,炎症的原因是什么?液态液态相隔离的方法信号传导的信号传导.

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