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Updated: Jan 18, 2026

Applying Live Cell Imaging and Cryo-Electron Tomography to Resolve Spatiotemporal Features of the Legionella pneumophila Dot/Icm Secretion System
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Applying Live Cell Imaging and Cryo-Electron Tomography to Resolve Spatiotemporal Features of the Legionella pneumophila Dot/Icm Secretion System

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一种VI型分泌系统输出的膜去极化毒素的冷EM结构,它参与了细菌对抗作用

Jake Colautti1, Dmitry Shatskiy2, Eileen M Bates1

  • 1Michael DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, ON L8S 4K1, Canada; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada.

Cell reports
|September 10, 2025
PubMed
概括

研究人员确定了Ptx2的结构,这是Pseudomonas aeruginosa细菌使用的有毒蛋白质. 这种VasX家族效应器在细胞膜中形成道,破坏细菌的功能.

关键词:
CP: 微生物学 微生物学科普:分子生物学 分子生物学伪omonas空气菌 伪omonas空气菌这是一种细菌毒素.低温电磁波冷却器 (Cryo-EM) 是一个非常好的方法.膜去极化毒素的产生孔隙形成的形成孔隙形成.第六类分泌系统.毒性因子是毒性因子.

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