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在冠状动脉分支病变中,使用一支或两支支支架的支架策略
Zachary Chan1, Michaella Alexandrou2, Dimitrios Strepkos2
1Cornell University, Ithaca, New York; Minneapolis Heart Institute and Minneapolis Heart Institute Foundation, Abbott Northwestern Hospital, Minneapolis, Minnesota.
The Journal of invasive cardiology
|September 10, 2025
概括
一个支架与两支支架在分叉穿皮冠状动脉干预 (PCI) 中显示了类似的长期结果. 这项研究比较了冠状动脉分支中PCI的1-stent和2-stent策略.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 医疗器械 医疗器械
背景情况:
- 穿皮冠状动脉干预 (PCI) 对于治疗冠状动脉疾病至关重要.
- 两叉病变在PCI中存在独特的挑战,通常需要复杂的支架策略.
- 在双叉PCI中,对1-stent与2-stent技术的比较结果数据仍然有限.
研究的目的:
- 为了比较手术特征和临床结果的前期1-stent与2-stent策略在双叉PCI.
- 评估长期随访结果,包括主要心脏不良事件 (MACE),用于两种支架方法.
主要方法:
- 从PROGRESS-BIFURCATION注册表 (2014-2024) 中分析了1306个分支的PCI.
- 分类为前期1支支支架 (主要是临时支架) 和前期2支支架策略 (例如,双吻粉碎,culotte).
- 血管造影,手术数据和临床结果的比较,平均随访时间长达3年.
主要成果:
- 在75.5%的病变中使用了前置1支支支架PCI,而在24.5%的病变中使用了2支架PCI.
- 两支支支架的策略与更长的手术/光学时间和更高的辐射剂量相关,但具有相似的对比度.
- 技术上的成功率高于2支支支架策略 (98.4% vs 94.4%),但程序上的成功率和医院内MACE的成功率相似.
- 在平均3年的随访期内,与1支支支架策略相比,使用2支架策略治疗的患者表现出类似的MACE,TVR,MI和全因死亡率.
结论:
- 前置1支干细胞和2支干细胞分支PCI技术显示了可比的程序成功和长期临床结果.
- 在选择1支支支架和2支支架的策略之间,应考虑病变的复杂性和程序因素,因为长期的结果似乎相似.
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