Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

The Cochlea01:13

The Cochlea

50.6K
The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
50.6K
Anatomy of the Ear01:16

Anatomy of the Ear

11.2K
Auditory sensation, commonly called hearing, involves the transformation of sonic waves into neural impulses facilitated by the structures of the auditory organ. The prominent, flesh-like structure on the side of the head, called the auricle, directs sound waves towards the auditory canal. The auricle is often mislabeled as the pinna, a term more aligned with mobile structures like a feline's external ear. The auditory canal penetrates the cranium via the external auditory meatus of the...
11.2K
Auditory Pathway01:15

Auditory Pathway

7.1K
Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...
7.1K
Hair Cells01:22

Hair Cells

44.4K
Hair cells are the sensory receptors of the auditory system—they transduce mechanical sound waves into electrical energy that the nervous system can understand. Hair cells are located in the organ of Corti within the cochlea of the inner ear, between the basilar and tectorial membranes. The actual sensory receptors are called inner hair cells. The outer hair cells serve other functions, such as sound amplification in the cochlea, and are not discussed in detail here.
44.4K
The Auditory Ossicles01:11

The Auditory Ossicles

3.0K
The auditory ossicles of the middle ear transmit sounds from the air as vibrations to the fluid-filled cochlea. The auditory ossicles consist of two malleus (hammer) bones, two incus (anvil) bones, and two stapes (stirrups), one on each side. These bones develop during the fetal stage and are the ones to ossify first. They are fully mature at birth and do not grow afterward.
The aptly named stapes look very much like a stirrup. The three ossicles are unique to mammals, and each plays a role in...
3.0K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Galectin and Myc enable cochlear progenitor expansion in vitro and in vivo.

bioRxiv : the preprint server for biology·2026
Same author

Epithelial-Mesenchymal Wnt Crosstalk Directs Planar Cell Polarity in the Developing Cochlea.

bioRxiv : the preprint server for biology·2026
Same author

Precise genetic control of ATOH1 enhances maturation of regenerated hair cells in the mature mouse utricle.

Nature communications·2024
Same author

Central Hearing Loss in a Pediatric Patient.

The Laryngoscope·2024
Same author

Single-cell transcriptomic atlas reveals increased regeneration in diseased human inner ear balance organs.

Nature communications·2024
Same author

β-Catenin transcriptional activity is required for establishment of inner pillar cell identity during cochlear development.

PLoS genetics·2023
Same journal

Towards globally equitable bioinformatics adoption.

PLoS biology·2026
Same journal

The human claustrum supports cognitive networks for externally and internally driven task demands.

PLoS biology·2026
Same journal

Unusual decay: Recombination loss leads to splicing errors in green algae.

PLoS biology·2026
Same journal

Angptl5 restricts primitive hematopoiesis by promoting retinoic acid signaling in zebrafish.

PLoS biology·2026
Same journal

Engineered bipaternal mice reveal the consequences of life without a maternal genomic contribution.

PLoS biology·2026
Same journal

Multiple adhesion molecules act together in oligodendrocyte-mediated axonal selection and myelin formation.

PLoS biology·2026
查看所有相关文章

相关实验视频

Updated: Jan 18, 2026

The Miniature Pig: A Large Animal Model for Cochlear Implant Research
06:16

The Miniature Pig: A Large Animal Model for Cochlear Implant Research

Published on: July 28, 2022

3.5K

隔间如何交谈:隔间合指导耳发育.

Ippei Kishimoto1, Alan G Cheng1

  • 1Otolaryngology-Head & Neck Surgery, Stanford University School of Medicine, Stanford, California, United States of America.

PLoS biology
|September 10, 2025
PubMed
概括
此摘要是机器生成的。

形态原体通过协调细胞区间之间的通信来指导内耳膜的发育. 这项研究揭示了平面细胞极性如何整合跨区域的信号,以便适当的器官形成.

更多相关视频

Long-term Time Lapse Imaging of Mouse Cochlear Explants
10:43

Long-term Time Lapse Imaging of Mouse Cochlear Explants

Published on: November 2, 2014

10.0K
Culture of Embryonic Mouse Cochlear Explants and Gene Transfer by Electroporation
09:03

Culture of Embryonic Mouse Cochlear Explants and Gene Transfer by Electroporation

Published on: January 12, 2015

13.4K

相关实验视频

Last Updated: Jan 18, 2026

The Miniature Pig: A Large Animal Model for Cochlear Implant Research
06:16

The Miniature Pig: A Large Animal Model for Cochlear Implant Research

Published on: July 28, 2022

3.5K
Long-term Time Lapse Imaging of Mouse Cochlear Explants
10:43

Long-term Time Lapse Imaging of Mouse Cochlear Explants

Published on: November 2, 2014

10.0K
Culture of Embryonic Mouse Cochlear Explants and Gene Transfer by Electroporation
09:03

Culture of Embryonic Mouse Cochlear Explants and Gene Transfer by Electroporation

Published on: January 12, 2015

13.4K

科学领域:

  • 发展生物学 发展生物学
  • 细胞生物学 细胞生物学
  • 有机体的产生.

背景情况:

  • 形态原体是指导胚胎发育的关键信号分子.
  • 内耳耳的形成涉及复杂的细胞相互作用.
  • 了解部门间的沟通是发展过程的关键.

研究的目的:

  • 为了研究不同区域区块在内耳耳发育过程中如何沟通.
  • 阐明平面细胞极性的作用在整合信号跨这些隔间.
  • 了解确保正确器官形态发生的机制.

主要方法:

  • 利用先进的成像技术可视化细胞行为.
  • 采用基因操纵来研究特定的信号通路.
  • 分析了不同耳区域内的细胞极性动态.

主要成果:

  • 证明平面细胞极性是跨区域区间协调的.
  • 确定了将细胞极性与区间间通信联系起来的特定分子机制.
  • 展示了这种整合如何对耳管形成至关重要.

结论:

  • 平面细胞极性作为一个关键的信息整合器,在发育中的尾细胞中跨越不同的细胞区.
  • 这种机制确保了适当的内耳形态发生所必需的协调细胞行为.
  • 这些发现为发育信号和器官形成提供了新的见解.