DST-3是一种新型的密度氨衍生物,通过CREB-Homer1轴激活减轻缺血性中风后的谷氨酸激发毒性

Yuxing Dai1, Jiaying Yu1, Gongyun He1

  • 1National and Local United Engineering Lab of Druggability and New Drugs Evaluation, Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Guangdong Province Engineering Laboratory for Druggability and New Drug Evaluation, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.

概括

与其前身cryptotanshinone相比,一种新的药物DST-3提供了针对缺血性中风的改善神经保护. DST-3通过CREB-Homer1通路调节谷氨酸刺激毒性和线粒体功能来起作用.

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