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Updated: Jan 18, 2026

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
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在人类B细胞封闭受体P2RY8中错觉变异的表型变性

Taylor N LaFlam1, Christian B Billesbølle2, Tuan Dinh3

  • 1Division of Pediatric Rheumatology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA; Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA, USA; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA, USA.

Cell genomics
|September 10, 2025
PubMed
概括

对P2RY8受体的深度突变扫描揭示了误解变异如何影响其功能. 整合结构和计算数据可以增强对这种G蛋白结合受体的理解.

关键词:
B 细胞 B 细胞 B 细胞在GPCR中,GPCR是指GPCR.在P2RY8中.低温电磁波冷却器 (Cryo-EM) 是一个非常好的方法.深度突变扫描 (deep mutational scanning) 是一种对突变进行深度扫描的方法.功能性基因组学 功能性基因组学淋巴瘤淋巴瘤是什么多重测定变异效应的多重测定.变体效应预测变体效应预测

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