家庭史指导的身体活动,用于预防心血管疾病
Ana Polo-López1, Joaquín Calatayud1, Laura López-Bueno1
1Exercise Intervention for Health Research Group (EXINH-RG), Department of Physiotherapy, University of Valencia, Valencia, Spain.
American journal of preventive medicine
|September 10, 2025
概括
患有心血管疾病家族史的个人可能会从中等到强烈的体力活动中体验到更大的心血管风险降低. 根据家族病史量身定制体育活动建议对于优化心血管健康至关重要.
科学领域:
- 心血管疾病的研究研究.
- 运动科学运动科学
- 公共卫生 公共卫生
背景情况:
- 心血管疾病 (CVD) 风险受到遗传学的影响.
- 家庭病史对身体活动降低心血管疾病风险的影响尚不清楚.
- 调查家族心血管疾病史在运动诱导风险降低中的作用至关重要.
研究的目的:
- 检查心血管疾病家族病史如何影响中度至强度体力活动 (MVPA) 与心血管疾病风险之间的关联.
- 为了确定具有家族心血管疾病病史的个体是否获得类似的心血管疾病发病率降低从MVPA相比,没有.
- 分析与家族病史有关的MVPA和事件心血管疾病之间的剂量反应关系.
主要方法:
- 使用英国生物银行进行的前性队列研究.
- 在一周内基于加速器测量MVPA的测量.
- 分析MVPA和事件心血管疾病之间的剂量反应关联,根据家族心血管疾病史分层.
主要成果:
- 分析了74,715名参与者,平均随访时间为7.9年.
- 对于那些有心血管疾病家族史的人来说,在每周10-1555分钟的MVPA之间观察到显著的风险降低,最佳降低在555分钟 (HR=0.72) 之间.
- 对于没有家族病史的人来说,显著的风险降低发生在每周220-555分钟的MVPA之间,最佳降低在445分钟 (HR=0.80) 之间.
结论:
- 家庭心血管疾病史影响中度至强度体力活动在降低心血管疾病风险方面的有效性.
- 患有心血管疾病家族史的个人可能会从较高量的MVPA中获益更多,以减少风险.
- 身体活动指南应考虑家族心血管疾病史,以提供个性化的建议.
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