Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Synthetic Biology02:55

Synthetic Biology

5.5K
Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
5.5K
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

989
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
989
Microbial Fermentation01:23

Microbial Fermentation

1.4K
Fermentation is a crucial anaerobic metabolic process that enables microbes to derive energy from sugar without relying on oxygen or an electron transport chain. This process is fundamental to various biological and industrial applications and is classified based on the metabolic products generated.Role of Pyruvate in FermentationPyruvate and its derivatives serve as key electron acceptors in fermentative pathways. The oxidation of NADH to regenerate NAD+ is essential for the continuation of...
1.4K
Environmental Applications of Microorganisms01:30

Environmental Applications of Microorganisms

995
Microorganisms play a pivotal role in maintaining ecosystem balance by recycling essential elements such as carbon, nitrogen, and phosphorus, as well as supporting processes like bioremediation, wastewater treatment, and biofuel production.Microbes in Elemental CyclesIn the carbon cycle, microorganisms decompose organic matter, releasing carbon dioxide via aerobic respiration. This carbon dioxide is subsequently used by photosynthetic organisms to synthesize organic compounds, closing the...
995
Microorganisms in Agriculture and Food industry01:27

Microorganisms in Agriculture and Food industry

1.4K
Microorganisms play a crucial role in agriculture and the food industry, contributing to soil fertility, crop protection, and food production. Their functions range from nitrogen fixation and biopesticide production to fermentation and food preservation, making them indispensable to sustainable farming and food safety.Role in AgricultureNitrogen-fixing bacteria, such as Rhizobium (symbiotic) and Azotobacter (free-living), convert atmospheric nitrogen into ammonia through biological nitrogen...
1.4K
Methods for Controlling Microbial Growth01:29

Methods for Controlling Microbial Growth

1.5K
Microbial growth control refers to various methods employed to inhibit, reduce, or eliminate microorganisms to ensure safety and hygiene across different settings. These methods are categorized based on the target environment and the level of microbial control required.Biocides are versatile agents designed to control microorganisms by either inhibiting their growth or outright killing them. These agents work through various physical, chemical, mechanical, or biological mechanisms. The...
1.5K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Sulfolobales: Acidothermophilic archaea as models for biology and biotechnological applications.

Engineering microbiology·2026
Same author

Comparative Analysis of Gut Microbiome Dynamics and Dietary Shifts in Three Pollinator Species During Alfalfa Pollination: Insights from Environmental DNA Metabarcoding.

Insects·2026
Same author

Profiling Protein Aggregate Size Using Single-Molecule Array Technology.

Analytical chemistry·2026
Same author

The impact of plant restoration on soil aggregates in karst mountainous areas of southwestern China.

iScience·2026
Same author

Determinants of childhood and adolescent obesity: An explainable AI approach using the ICAD database.

Public health·2026
Same author

Fermented feed-rumen microbiota axis mediates goat kid growth via microbial amino acid synthesis and ruminal epithelial energy metabolism.

NPJ biofilms and microbiomes·2026

相关实验视频

Updated: Jan 18, 2026

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology
06:24

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology

Published on: December 15, 2017

10.6K

利用人工智能实现高效的微生物生产.

Xinyu Gong1, Jianli Zhang1, Qi Gan1

  • 1School of Chemical, Materials and Biomedical Engineering, College of Engineering, the University of Georgia, College of Engineering, Athens, GA 30602, USA.

Bioresource technology
|September 10, 2025
PubMed
概括
此摘要是机器生成的。

人工智能 (AI) 通过克服酶发现,代谢调节和生物过程控制方面的局限性来增强微生物生产. 蛋白质工程和生物工艺开发中的AI应用正在加速可持续的化合物制造.

关键词:
人工智能的人工智能是人工智能.生物过程控制 生物过程控制微生物生产的微生物生产.蛋白质采矿和工程 蛋白质采矿和工程

更多相关视频

Use of High-Throughput Automated Microbioreactor System for Production of Model IgG1 in CHO Cells
08:15

Use of High-Throughput Automated Microbioreactor System for Production of Model IgG1 in CHO Cells

Published on: September 28, 2018

11.4K
Automated Microbial Cultivation and Adaptive Evolution using Microbial Microdroplet Culture System MMC
08:18

Automated Microbial Cultivation and Adaptive Evolution using Microbial Microdroplet Culture System MMC

Published on: February 18, 2022

4.5K

相关实验视频

Last Updated: Jan 18, 2026

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology
06:24

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology

Published on: December 15, 2017

10.6K
Use of High-Throughput Automated Microbioreactor System for Production of Model IgG1 in CHO Cells
08:15

Use of High-Throughput Automated Microbioreactor System for Production of Model IgG1 in CHO Cells

Published on: September 28, 2018

11.4K
Automated Microbial Cultivation and Adaptive Evolution using Microbial Microdroplet Culture System MMC
08:18

Automated Microbial Cultivation and Adaptive Evolution using Microbial Microdroplet Culture System MMC

Published on: February 18, 2022

4.5K

科学领域:

  • 生物技术和合成生物学
  • 生物工艺工程 生物工艺工程
  • 计算生物学 计算生物学

背景情况:

  • 微生物生产为有价值的化合物提供了可持续的途径,但面临着诸如有限的酶和低于最佳的过程等挑战.
  • 关键的瓶包括不足的功能性酶用于途径的构建和不足的工具用于代谢调节和生物过程优化.
  • 这些局限性阻碍了工业微生物制造的效率和可扩展性.

研究的目的:

  • 审查最近人工智能 (AI) 应用在微生物生产方面的进展.
  • 突出AI在解决酶发现,菌株开发和生物过程优化方面的挑战中的作用.
  • 提出人工智能在微生物制造中的整合未来方向.

主要方法:

  • 用人工智能驱动的蛋白质采矿用于新型酶识别.
  • 人工智能辅助的蛋白质工程,以改善酶功能和稳定性.
  • 机器学习模型用于预测菌株表型和优化发酵条件.
  • 在上游生物工艺开发管道中整合AI工具.

主要成果:

  • 人工智能显著改善了微生物通路的功能酶的发现和工程.
  • 人工智能提供了对菌株表型和发酵参数的预测洞察力,提高了生产力.
  • 人工智能有助于开发更强大,更有效的微生物细胞工厂.
  • 人工智能简化了上游生物工艺开发,加速了微生物产品的上市时间.

结论:

  • 人工智能技术对于克服微生物生产现有的局限性至关重要.
  • 人工智能驱动的方法提高了酶能力,代谢控制和生物过程效率.
  • 人工智能的未来发展和应用将进一步彻底改变可持续的微生物制造.