在自闭症谱系障碍中,社交导航的神经跟踪
Sarah M Banker1, Matthew Schafer2, Sarah Barkley3
1Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York; Center for Computational Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York; Seaver Autism Center for Research and Treatment, Icahn School of Medicine at Mount Sinai, New York, New York; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York; Department of Child and Adolescent Psychiatry, New York University Medical Center, New York, New York.
Biological psychiatry
|September 10, 2025
概括
患有自闭症谱系障碍 (ASD) 的成年人表现出明显的社会行为和神经活动,但核心的社会映射大脑系统似乎被保留了. 这突出了共享和ASD特定的社交导航机制.
科学领域:
- 神经科学是一个神经科学.
- 社会认知是指社会认知.
- 临床心理学 临床心理学
背景情况:
- 自闭症谱系障碍 (ASD) 与影响社会信息处理的社会挑战有关.
- 了解自闭症成年人的社会认知映射对于导航社会动态至关重要.
- 在自闭症成年人群中对社会认知映射的研究有限.
研究的目的:
- 研究自闭症成年人和神经类型个体之间的社会导航和认知映射的差异.
- 探索自闭症谱系障碍 (ASD) 中社会决策的神经基础.
- 为了比较具有自闭症,典型发育 (TD) 和失声症 (MIS) 的成年人的社会行为和大脑活动.
主要方法:
- 功能性磁共振成像 (fMRI) 在社交互动任务中被采用.
- 122名成年人参与了这项研究:122名成年人患有自闭症,典型发育 (TD) 和失声症 (MIS).
- 分析了行为和神经数据,以比较社会距离跟踪和大脑活动.
主要成果:
- 与TD和MIS组相比,患有自闭症的成年人表现出更社会疏远的行为.
- 在不同组的关键大脑区域 (PCC,PPA) 观察到可比的社交距离神经跟踪.
- 自闭症组在极 (TP) 中表现出低活性,这与社会回避和较小的社交网络有关.
结论:
- 自闭症成年人在社会决策过程中表现出独特的行为和神经模式.
- 在ASD,TD和MIS群体中,社交映射的核心大脑系统似乎完好无损.
- 研究结果揭示了社交导航中的共同和ASD特有的神经机制,为理解ASD中的社会证据处理提供了信息.
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