NFATc3PMLSUMOylation-Independent

Ting Kang1, Ruizhe Huang1, Ruiheng Wang2

  • 1Department of Oncology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200092, China.

Biochimie
|September 10, 2025
PubMed
概括

在癌症中,激活T细胞3核因子 (NFATc3) 和原血细胞白血病蛋白 (PML) 之间的相互作用是独立于SUMOylation的. 这个轴调节Lgr5和Olfm4,硫化物显示出作为调节器的潜力.

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